Keep calm and reboot – how cells restart transcription after DNA damage and DNA repair
Donnio LM, Giglia-Mari G.
FEBS. 2024 Jul
Decline of DNA damage response along with myogenic differentiation
Sutcu H, Rassinoux P, Donnio LM, Neuillet D, Vianna F, Gabillot O, Mari PO, Baldeyron C, Giglia-Mari G.
Life Science Alliance. 2023 Nov
Nucleolar Reorganizaton after cellular stress is orchestrated by SMN shuttling between nuclear compartments
Musawi S, Donnio LM, Zhao Z, Magnani C, Rassinoux P, Binda O, Huang J, Jacquier A, Coudert L, Lomonte P, Martinat C, Schaeffer L, Mottet D, Côté J, Mari PO, Giglia-Mari G.
Nature Communications. 2023 Nov
XAB2 Dynamics during DNA Damage-Dependent Transcription Inhibition
Donnio LM, Cerutti E, Magnani C, Neuillet D, Mari PO, Giglia-Mari G.
Elife. 2022 Jul
A stable XPG protein is required for proper ribosome biogenesis: Insights on the phenotype of combinate Xeroderma Pigmentosum/Cockayne Syndrome patients.
Taupelet F, Donnio LM, Magnani C, Mari PO, Giglia-Mari G.
PLoS One. 2022 Jul
Actin and Nuclear Myosin I are responsible for nucleolar reorganization during DNA Repair
Cerutti E , Daniel L, Donnio LM, Neuillet D, Magnani C, Mari PO, Giglia-Mari G.
BioRXiv.
Cell-type specific concentration regulation of the basal transcription factor TFIIH in XPBy/y mice model.
Donnio LM, Miquel C, Vermeulen W, Giglia-Mari G, Mari PO.
Cancer Cell International. 2019 Sep
CSB-Dependent Cyclin-Dependent Kinase 9 Degradation and RNA Polymerase II Phosphorylation during Transcription-Coupled Repair.
Donnio LM, Lagarou A, Sueur G, Mari PO, Giglia-Mari G.
Molecular and Cellular Bioliolgy. 2019 Mar
Mechanistic insights in transcription-coupled nucleotide excision repair of ribosomal DNA.
Daniel L, Cerutti E, Donnio LM, Nonnekens J, Carrat C, Zahova S, Mari PO, Giglia-Mari G.
Proceedings of the National Academy of Sciences U S A. 2018 Jul
Small molecule-based targeting of TTD-A dimerization to control TFIIH transcriptional activity represents a potential strategy for anticancer therapy.
Gervais V, Muller I, Mari PO, Mourcet A, Movellan KT, Ramos P, Marcoux J, Guillet V, Javaid S, Burlet-Schiltz O, Czaplicki G, Milon A, Giglia-Mari G.
Journal of Biological Chemistry. 2018 Sep
ELL, a novel TFIIH partner, is involved in transcription restart after DNA repair.
Mourgues S, Gautier V, Lagarou A, Bordier C, Mourcet A, Slingerland J, Kaddoum L, Coin F, Vermeulen W, Gonzales de Peredo A, Monsarrat B, Mari PO, Giglia-Mari G.
Proceedings of the National Academy of Sciences U S A. 2013 Oct
In vivo interactions of TTDA mutant proteins within TFIIH.
Nonnekens J, Cabantous S, Slingerland J, Mari PO, Giglia-Mari G.
Journal of Cell Science. 2013 Aug
Mutations in TFIIH causing trichothiodystrophy are responsible for defects in ribosomal RNA production and processing.
Nonnekens J, Perez-Fernandez J, Theil AF, Gadal O, Bonnart C, Giglia-Mari G.
Human Molecular Genetics. 2013 Jul
Generation of DNA single-strand displacement by compromised nucleotide excision repair.
Godon C, Mourgues S, Nonnekens J, Mourcet A, Coin F, Vermeulen W, Mari PO, Giglia-Mari G.
EMBO Journal. 2012 Aug
Slowly progressing nucleotide excision repair in trichothiodystrophy group A patient fibroblasts.
Theil AF, Nonnekens J, Wijgers N, Vermeulen W, Giglia-Mari G.
Molecular Cell Biology. 2011 Sep
DNA damage response.
Giglia-Mari G, Zotter A, Vermeulen W.
Cold Spring Harbor Perspectives in Biology. 2011 Jan
Collaborations
H2A.Z is involved in premature aging and DSB repair initiation in muscle fibers.
Belotti E, Lacoste N, Iftikhar A, Simonet T, Papin C, Osseni A, Streichenberger N, Mari PO, Girard E, Graies M, Giglia-Mari G, Dimitrov S, Hamiche A, Schaeffer L.
Nucleic Acids Research. 2024 Apr
Active mRNA degradation by EXD2 nuclease elicits recovery of transcription after genotoxic stress
Sandoz J, Cigrang M, Zachayus A, Catez P, Donnio LM, Elly C, Nieminuszczy J, Berico P, Braun C, Alekseev S, Egly JM, Niedzwiedz W, Giglia-Mari G, Compe E, Coin F.
Nature Communications. 2023 Jan
Active DNA damage eviction by HLTF stimulates nucleotide excision repair.
van Toorn M, Turkyilmaz Y, Han S, Zhou D, Kim HS, Salas-Armenteros I, Kim M, Akita M, Wienholz F, Raams A, Ryu E, Kang S, Theil AF, Bezstarosti K, Tresini M, Giglia-Mari G, Demmers JA, Schärer OD, Choi JH, Vermeulen W, Marteijn JA.
Molecular Cell. 2022 Apr
A ubiquitylation site in Cockayne syndrome B required for repair of oxidative DNA damage, but not for transcription-coupled nucleotide excision repair.
Ranes M, Boeing S, Wang Y, Wienholz F, Menoni H, Walker J, Encheva V, Chakravarty P, Mari PO, Stewart A, Giglia-Mari G, Snijders AP, Vermeulen W, Svejstrup JQ.
Nucleic Acids Research. 2016 Jun
Differential binding kinetics of replication protein A during replication and the pre- and post-incision steps of nucleotide excision repair.
Gourdin AM, van Cuijk L, Tresini M, Luijsterburg MS, Nigg AL, Giglia-Mari G, Houtsmuller AB, Vermeulen W, Marteijn JA.
DNA Repair (Amst). 2014 Dec
Isoform-specific anti-MeCP2 antibodies confirm that expression of the e1 isoform strongly predominates in the brain.
Kaddoum L, Panayotis N, Mazarguil H, Giglia-Mari G, Roux JC, Joly E.
F1000Res. 2013 Oct
Histone methyltransferase DOT1L drives recovery of gene expression after a genotoxic attack.
Oksenych V, Zhovmer A, Ziani S, Mari PO, Eberova J, Nardo T, Stefanini M, Giglia-Mari G, Egly JM, Coin F.
PLoS Genetics. 2013 Jul
DNA repair: a changing geography? (1964-2008).
Maisonobe M, Giglia-Mari G, Eckert D.
DNA Repair (Amst). 2013 Jul
Disruption of TTDA results in complete nucleotide excision repair deficiency and embryonic lethality.
Theil AF, Nonnekens J, Steurer B, Mari PO, de Wit J, Lemaitre C, Marteijn JA, Raams A, Maas A, Vermeij M, Essers J, Hoeijmakers JH, Giglia-Mari G, Vermeulen W.
PLoS Genetics. 2013 Apr
Kinetics of endogenous mouse FEN1 in base excision repair.
Kleppa L, Mari PO, Larsen E, Lien GF, Godon C, Theil AF, Nesse GJ, Wiksen H, Vermeulen W, Giglia-Mari G, Klungland A.
Nucleic Acids Research. 2012 Oct
DNA in 3R: Repair, Replication, and Recombination.
Coin F, Reina-San-Martin B, Giglia-Mari G, Berneburg M.
Molecular Biology International. 2012 Mar